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Data: Fair

Iodopropynyl Butylcarbamate

IMAGE SOURCE: PubChem

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Other Concerns

Use restrictions (high), Persistence and bioaccumulation (moderate), and Non-reproductive organ system toxicity (low)

SYNONYMS

● DTXSID0028038
● KS-00000LXO
● ZINC1850357
● TOX21_301117
● AKOS015905567
● 3-IODO-2-PROPYNYL N-BUTYLCARBAMATE, ANALYTICAL STANDARD
● TOX21_201864
● ANW-44089
● GS-3240
● 3-IODO-2-PROPYNYL BUTYLCARBAMATE #

Unacceptable

Unacceptable: EWG VERIFIED products cannot contain this ingredient


Iodopropynyl butylcarbamate is used as a preservative in cosmetic formulations; it is acutely toxic by inhalation and should not be used in products that can be aerosolized or inhaled.

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • MODERATE
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • HIGH
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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anti-aging19 products
body firming lotion14 products
around-eye cream12 products
muscle/joint soreness2 products
facial moisturizer/treatment61 products
conditioner192 products
detangler12 products
styling mousse/foam19 products
styling gel/lotion172 products
hair spray21 products
facial cleanser59 products
toners/astringents7 products
foot moisturizer15 products
hand cream17 products
moisturizer66 products
mask87 products
exfoliant/scrub67 products
shaving cream (men's)6 products
serums & essences31 products
shampoo157 products
after shave10 products
hair styling aid168 products
sunless tanning4 products
body wash/cleanser168 products
hair treatment/serum112 products
eye liner51 products
shaving cream4 products
skin fading/lightener2 products
Putties, Puddings & Clays2 products
hair relaxer3 products
baby wipes36 products
makeup remover62 products
Beard Soaps1 products
liquid hand soap87 products
eye makeup remover6 products
hair color and bleaching22 products
recreational sunscreen7 products
hand sanitizer6 products
after sun product14 products
foot cleansing7 products
Bath and Body Wipes6 products
mascara11 products
foundation98 products
Hair Styling Gel20 products
daily use with SPF16 products
Facial Sun Care2 products
beard cleanser2 products
eye shadow28 products
beard care4 products
concealer19 products
brow liner14 products
body oil3 products
glitter6 products
nail polish1 products
makeup primer11 products
setting powder/spray1 products
tanning oil1 products
bubble bath4 products
CC cream5 products
hair removal waxes1 products
body spray6 products
Wipes5 products
foot odor control1 products
bath oil/salts/soak5 products
personal cleansing1 products
beard oil1 products
lipstick7 products
bronzer/highlighter11 products
lip balm1 products
Oils & Serums2 products
nail treatment1 products
antiperspirant/deodorant1 products
Face Wipes1 products
Exfoliants1 products
BB cream1 products

Allergies/immunotoxicity

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CONCERN REFERENCE
One or more human case studies show significant immune or allergenic effectsAllergic contact dermatitis from 3-iodo-2-propynyl-butylcarbamate in a cosmetic cream(1999-11-01)
Human any toxicant or allergen - strong evidenceCosmetic Ingredient Review (CIR)

Data gaps

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CONCERN REFERENCE
Safety assessment was based on related chemicalCosmetic Ingredient Review (CIR)

Use restrictions

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CONCERN REFERENCE
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR)Cosmetic Ingredient Review (CIR)
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review (CIR)
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)Japan Ministry of Health
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - prohibited for use in some types of cosmeticsJapan Ministry of Health

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR)Cosmetic Ingredient Review (CIR)

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as not expected to be potentially toxic or harmfulEnvironment Canada
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)Environmental Protection Agency (EPA)

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be persistentEnvironment Canada
Not suspected to be bioaccumulativeEnvironment Canada
Persistent or bioaccumulative and moderate to high toxicity concern in humansOrganohalogen Pollutants and Human Health(2017-01-01)

Ecotoxicology

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CONCERN REFERENCE
Suspected to be an environmental toxinEnvironment Canada
  • Allergic contact dermatitis from 3-iodo-2-propynyl-butylcarbamate in a cosmetic cream(1999-11-01)
  • Cosmetic Ingredient Review (CIR)
  • Japan Ministry of Health
  • Environment Canada
  • Environmental Protection Agency (EPA)
  • Organohalogen Pollutants and Human Health(2017-01-01)

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.


HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG Verified® mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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